From Embryology to Biological Infrastructure
SABC is initiated and led by experienced experts in the field of modern embryonic biotechnology, updating the world's technology progress following embryo transfer, embryo cryopreservation, in vitro embryo production, and somatic cloning in the 80s and 90s of the twentieth century to today’s cutting-edge stem cell and gene-based innovation


Milestones Achievements
1978–1986 | Embryo Biotechnology Pioneer
Achieved the first successful embryo transfer in an experimental animal (1978) and a domestic animal (1986), establishing the scientific foundation for advanced reproductive biotechnology and embryo engineering.
1983 | Breakthrough in Cryobiology
Developed the world's first successful rapid embryo freezing technology following room-temperature dehydration, marking a major milestone in cryopreservation science and laying the foundation for future biobanking technologies.
1998–2000 | Somatic Cloning & Cell Reprogramming
Pioneered interspecies somatic cell nuclear transfer (SCNT) in endangered wildlife species, advancing cloning technologies for both biodiversity conservation and regenerative biology.
1999 | Human Reproductive Medicine
Established one of Vietnam's earliest clinical semen cryobanking programs and successfully translated cryobiology into human assisted reproductive medicine.
2000-2012 | Advanced Embryo Cryopreservation
Achieved the first successful vitrification of somatic cloning embryos, expanding the technological foundation for cloning, stem cell science, and regenerative medicine. Successful initial cryopreservation of Sutchi Catfish and black tiger shrimp embryos has been achieved
2002 | In Vitro Embryo Production Innovation
Successfully produced, sexed, and transferred in vitro fertilized embryos, advancing reproductive biotechnology and embryo production technologies.
2006–2015 | Biodiversity Infrastructure Development
Expanded core cryobiology and reproductive technologies into biodiversity conservation through strategic collaboration with the Viet–France Biodiversity Program (Biodiva) and JICA. During this period, integrated capabilities in wildlife reproduction, genetic resource preservation, cryobanking, and conservation biotechnology were established, forming the foundation of SABC's Biodiversity Infrastructure.
2008–2015 | Stem Cell Biotechnology & Cell Banking
Established pioneering capabilities in mesenchymal stem cell (MSC) isolation, cryopreservation, expansion, and differentiation. These achievements led to the development of stem cell banking and early translational platforms supporting regenerative medicine.
2010–Present | Clinical Translation & Cell Banking
Implemented stem cell banking technologies and clinical applications in collaboration with leading hematology, obstetrics, blood transfusion, and oncology hospitals, creating a translational platform for next-generation Cell & Gene Therapy (CGT).
2015–Present | Building the SABC Integrated Biological Infrastructure (SABC-IBI)
Initiated the development of the SABC Integrated Biological Infrastructure (SABC-IBI), integrating cryobiology, reproductive biology, stem cell science, genetics, digital technologies, and AI into a unified regional platform. The Biodiversity Infrastructure for biological resource conservation and the SABC-HLP Human Health Infrastructure, supporting regenerative medicine, advanced biomanufacturing, and precision healthcare across Southeast Asia.
SABC experts and collaborators have chaired and participated in many national and international projects working on the application of technological innovations for improving biodiversity conservation, livestock development and for biomedicine.
Research projects
National projects R&D in Embryo Biotechnology (470107, 1980-1985; 52D-0113,1986-1990;KC-08-16); Vietnam National Foundation for Science and Technology Development (NAFOSTED) project on somatic cloning;
project of cooperation with AIRE Development and INRA French on cryobiology and embryo preservation, embryo transfer; project for Promotion of Basic Research Activities for Innovative Biosciences (PROBRAIN), Japan for somatic cloning and vitrification cryopreservation; Vietnam_Italy Project on development of reproductive technology in buffalo; Vietnam-USA project on in vitro fertilization sexing and intercontionental embryo transfer.
MOST Project ĐTĐL 2007/03 for differentiation of human umbilical cord matrix stem cell into neural and cardiac progenitor cells; Viet-Thailand project on induction of corneal epithelial cells;
https://rep.bioscientifica.com/view/journals/rep/71/2/jrf_71_2_032.xml?rskey=b49amE&result=4; https://pubmed.ncbi.nlm.nih.gov/16725971/
DOI: 10.1016/0093-691x(84)90459-x
https://pubmed.ncbi.nlm.nih.gov/10898213/
https://www.publish.csiro.au/rd/RDv19n1Ab93
https://pubmed.ncbi.nlm.nih.gov/25474756/
Transfer technology and Development project
Project supported by AIRE-Developpement (International Agency for Research and Study for Development, French), INRA French, Bomed-USA for implementation of embryo biotechnology in domestic animal breeding.
Project Biodiva Supported by FSP (Fonds de solidarité prioritaire), FFEM (Fonds français pour l'environnement mondial), CIRAT Centre de Coopération Internationale en Recherche Agronomique pour le Développement) and INRA for "Inventory, characterization and promotion of domestic animal biodiversity and wilderness of the Annamitic Cordillera in Vietnam, for conservation and sustainable development", improvement of somatic Cloning of wild Saola and Gaur, cryobank management and development of in situ - ex situ links.
JSPS-Japan-VAST Vietnam Project for application vitro production, manipulation and preservation of porcine embryos of Vietnam's native pig breeds for the conservation of biodiversity in pigs.
Project 01C-05/04-2016-3, supported by HanoiDOST. Main objective: Developing technique of reproductive management for improving rabbit production.
https://pigtrop.cirad.fr/content/download/2581/13171/file;https://www.publish.csiro.au/RD/RDv16n1Ab259;https://www.publish.csiro.au/rd/ExportCitation/rdv17n2ab56; https://www.publish.csiro.au/RD/RDv16n1Ab259)
https://123dok.net/article/la-production-scientifique-et bibliographique.qvl9g9ng;
https://agris.fao.org/agris-search/search.do?recordID=FR2013104863
